C-kit Expression Distinguishes Salivary Gland Adenoid Cystic Carcinoma from Polymorphous Low-Grade Adenocarcinoma
نویسندگان
چکیده
منابع مشابه
C-kit expression in the salivary gland neoplasms adenoid cystic carcinoma, polymorphous low-grade adenocarcinoma, and monomorphic adenoma.
OBJECTIVE Differentiating between adenoid cystic carcinomas (ACCs), polymorphous low-grade adenocarcinomas (PLGAs), and the monomorphic adenomas (including canalicular adenomas, trabecular adenomas, and basal cell adenomas) can present a diagnostic challenge, especially when examining tissue obtained from small incisional or fragmented biopsies. Recent studies have revealed that overexpression ...
متن کاملDiagnostic utility of C-kit protein (CD117) expression in differentiating adenoid cystic carcinoma and polymorphous low grade Adenocarcinoma
Background & Objective To evaluate usefulness of immunohistochemical marker C-kit (CD117) in differentiating Adenoid cystic carcinoma (AdCC) from Polymorphous low-grade adenocarcinoma (PLGA) in patients of salivary gland carcinomas. AdCC is a malignant salivary gland neoplasm with poor prognosis. PLGA is a salivary gland malignancy with indolent growth pattern. Differentiating between the two e...
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to study the immunohistochemical pattern of cd 117, glial fibrillary acidic protein (gfap), smooth muscle actin (sma) and cd 43 in pleomorphic adenoma (pa), adenoid cystic carcinoma (adcc) and polymorphous low grade adenocarcinoma (plga) of minor salivary glands.twenty cases of pa, 20 cases of adcc and 10 cases of plga were retrieved from record files along with their paraffin blocks at armed f...
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background and aim: salivary gland tumors classification continuously undergoes alternations, especially in the recent years. this study used immunohistochemical markers for distinguishing between polymorphous low-grade adenocarcinoma (plga) and adenocarcinoma carcinoma (adcc) which have several overlapping histological and clinical features. materials & methods: ten adcc and eight plga with fi...
متن کاملImmunohistochemical Pattern of Pleomorphic Adenoma, Polymorphous Low Grade Adenocarcinoma and Adenoid Cystic Carcinoma in Minor Salivary Glands
OBJECTIVE To study the immunohistochemical pattern of CD 117, glial fibrillary acidic protein (GFAP), smooth muscle actin (SMA) and CD 43 in pleomorphic adenoma (PA), adenoid cystic carcinoma (AdCC) and polymorphous low grade adenocarcinoma (PLGA) of minor salivary glands. MATERIALS AND METHODS Twenty cases of PA, 20 cases of AdCC and 10 cases of PLGA were retrieved from record files along wi...
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ژورنال
عنوان ژورنال: Modern Pathology
سال: 2002
ISSN: 0893-3952,1530-0285
DOI: 10.1097/01.mp.0000018973.17736.f8